发明名称 |
METHOD OF DETERMINING IMMUNE ENHANCEMENT OF VIRUS INFECTIVITY USING FC RECEPTOR-TRANSFECTED CELL LINES |
摘要 |
The present invention relates to a method of detecting immune enhancement of virus infectivity, a method of determining neutralization and immune enhancement of virus infectivity, a method of identifying a virus epitope that displays immune enhancement, a method of identifying a compound that modulates activity of an Fc receptor, and a method of identifying a compound that modulates intracellular signaling of an Fc receptor. DNA constructs, cells, and kits relating to these assays are also disclosed.
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申请公布号 |
CA2610619(A1) |
申请公布日期 |
2006.12.07 |
申请号 |
CA20062610619 |
申请日期 |
2006.05.31 |
申请人 |
UNIVERSITY OF ROCHESTER |
发明人 |
SCHLESINGER, JACOB J.;ROSE, ROBERT C.;JIN, XIA;RODRIGO, SHANAKA W. W. |
分类号 |
C12Q1/70;A61K39/12;A61K39/42 |
主分类号 |
C12Q1/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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