摘要 |
PROBLEM TO BE SOLVED: To provide a technology for purifying a poly(A)RNA having a high purity efficiently from a specimen containing nucleic acids such as a cell, etc., and a method for preparing the poly(A)RNA based on the effect of an electric field impression on a polyadenine molecule. SOLUTION: This method is to change the dipole moment and orientation of the polyadenine molecules by impressing the electric field in a reaction field. Thereby, by impressing the electric field in the reaction field, it is possible to accelerate the complement fixation of a dT chain with the poly(A) chain of the poly(A)RNA, or accelerate the addition and/or elongation of the poly(A) chain to the 3'terminal site of the RNA. COPYRIGHT: (C)2007,JPO&INPIT
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