| 发明名称 |
Nitoroxy derivatives of losartan, valsatan, candesartan, telmisartan, eprosartan and olmesartan as angiotensin-II receptor blockers for the treatment of cardiovascular diseases |
| 摘要 |
Angiotensin II receptor blocker nitroderivatives of formula (I): <?in-line-formulae description="In-line Formulae" end="lead"?>R-(Y-ONO<SUB>2</SUB>)<SUB>s</SUB> (I) <?in-line-formulae description="In-line Formulae" end="tail"?> having wider pharmacological activity and enhanced tolerability. They can be employed for treating cardiovascular, renal and chronic liver diseases and inflammatory processes.
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| 申请公布号 |
US2006276523(A1) |
申请公布日期 |
2006.12.07 |
| 申请号 |
US20040566292 |
申请日期 |
2004.07.20 |
| 申请人 |
ALMIRANTE NICOLETTA;DEL SOLDATO PIERO;ONGINI ENNIO |
发明人 |
ALMIRANTE NICOLETTA;DEL SOLDATO PIERO;ONGINI ENNIO |
| 分类号 |
A61K31/4184;A61K31/4178;A61K31/60;C07D235/20;C07D257/04;C07D403/02;C07D403/10;C07D409/02;C07D409/06 |
主分类号 |
A61K31/4184 |
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