发明名称 |
Pharmaceutical compositions for treating or preventing coronary artery disease |
摘要 |
The present invention provides pharmaceutical compositions and methods for raising plasma levels of apolipoprotein A-I in a mammal, e.g. for treating or preventing coronary artery disease (CAD). The inventive pharmaceutical compositions comprise: (a) a negatively charged phospholipid; and (b) at least one intestinal absorption enhancer; where (a) and (b) are present in such composition in amounts that render the combination effective for raising plasma levels of apolipoprotein A-I in a mammal. Also provided are corresponding methods of medical treatment comprising administering to a mammal: (a) a negatively charged phospholipid; and (b) at least one intestinal absorption enhancer; where (a) and (b) are administered in amounts that render the combination effective for raising plasma levels of apolipoprotein A-I in said mammal.
|
申请公布号 |
US2006275356(A1) |
申请公布日期 |
2006.12.07 |
申请号 |
US20060438334 |
申请日期 |
2006.05.23 |
申请人 |
BURGESS JAMES W;SPARKS DANIEL L;SINCLAIR PHILIP A |
发明人 |
BURGESS JAMES W.;SPARKS DANIEL L.;SINCLAIR PHILIP A. |
分类号 |
A61K31/401;A61K9/127;A61K31/22;A61K31/366 |
主分类号 |
A61K31/401 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|