发明名称 |
NOVEL FORMS OF FLUVASTATIN SODIUM, PROCESSES FOR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF |
摘要 |
Provided are substantially amorphous fluvastatin sodium and amorphous Form R6 and R-14 of fluvastatin sodium. Also provided are crystalline forms of fluvastatin sodium designated as Forms R-1, R-2, R-3, R-4, R-5, R-7, R-8, R-9, R-10, R-11, R-12, R-13, R-15 and R-16 and an anhydrous crystalline form. Also provided are processes for preparing such polymorphic forms and pharmaceutical compositions thereof. Also provided are methods for antagonizing HMG-CoA comprising administering to a mammal therapeutically effective amounts of the compounds described herein. |
申请公布号 |
WO2006030304(A3) |
申请公布日期 |
2006.12.07 |
申请号 |
WO2005IB02754 |
申请日期 |
2005.09.16 |
申请人 |
RANBAXY LABORATORIES LIMITED;DE, SHANTANU;TRIPATHI, VINAYAK;SATHYANARAYANA, SWARGAM;JINDAL, SHANTANU;KUMAR, YATENDRA |
发明人 |
DE, SHANTANU;TRIPATHI, VINAYAK;SATHYANARAYANA, SWARGAM;JINDAL, SHANTANU;KUMAR, YATENDRA |
分类号 |
C07D209/24;A61K31/404 |
主分类号 |
C07D209/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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