发明名称 |
METHOD OF DIAGNOSING APOPLECTIC STROKE/ASYMPTOMATIC BRAIN INFARCTION USING POLYAMINE AND ACROLEIN CONTENTS, POLYAMINE OXIDASE ACTIVITY OR PROTEIN CONTENT THEREOF AS INDICATION |
摘要 |
The present invention provides a diagnostic method for stroke/asymptomatic cerebral infarction and a screening method for patients with stroke/asymptomatic cerebral infarction, which comprise measuring acrolein content or polyamine content; or polyamine oxidase activity or protein content of polyamine oxidase in plasma. The knowledge of the present invention indicates the possibility of preventing, inhibiting the progression of stroke/asymptomatic cerebral infarction by inhibiting polyamine oxidase, and the possibility of obtaining a therapeutic agent for stroke/asymptomatic cerebral infarction by searching for compounds that inhibit polyamine oxidase.
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申请公布号 |
EP1729129(A1) |
申请公布日期 |
2006.12.06 |
申请号 |
EP20050727387 |
申请日期 |
2005.03.25 |
申请人 |
FUENCE CO. LTD.;AMINE PHARMA RESEARCH INSTITUTE |
发明人 |
IGARASHI, KAZUEI;UEDA, SHIRO;SAEKI, NAOKATSU;KASHIWAGI, KEIKO;TOMITORI, HIDEYUKI |
分类号 |
G01N33/50;C12Q1/26;G01N33/68 |
主分类号 |
G01N33/50 |
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