| 摘要 |
This invention provides 19-nor-D- homosteroids, having a mixed androgenic/progestagenic profile, which are orally active, prevent trabecular bone mineral density (BMD) loss, and which lack liver toxicity, having a structure according to the formula (I) wherein, R1 is O, or NOR, with R being hydrogen, (Cl-6) alkyl or (Cl-6)acyl, R2 is methyl or ethyl, and R3 is hydrogen or (C1-15)acyl.
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