| 摘要 |
[PROBLEMS] To provide a novel quinolonecarboxylic acid compound which is safe, has potent antibacterial activity, and is effective against resistant bacteria which are less controlled by conventional antibacterials. [MEANS FOR SOLVING PROBLEMS] It is a 7-(4-substituted 3-cyclopropylaminomethylpyrrolidinyl) quinolonecarboxylic acid derivative represented by the general formula (I) (typical example: 1-cyclopropyl-7-[(3S,4S)-cyclopropyl-aminomethyl-4- fluoro-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3- quinolinecarboxylic acid). The derivative has potent antibacterial activity against gram-positive bacteria, in particular, resistant bacteria such as MRSA, PRSP, and VRE, and is highly safe.
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