发明名称 |
QUINOLINE DERIVATIVES USEFUL AS MODULATORS OF ION CHANNELS |
摘要 |
<p>The present invention relates to compounds of formula (I-A), formula (I-B), formula (I-C) or formula (I-D), or a pharmaceutically acceptable salt thereof, wherein R<SUP>1</SUP>-R<SUP>3</SUP>,R<SUP>5</SUP> W, X and Y are as defined in claim 1 useful as inhibitors of ion channels.The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.</p> |
申请公布号 |
WO2006127329(A1) |
申请公布日期 |
2006.11.30 |
申请号 |
WO2006US18872 |
申请日期 |
2006.05.15 |
申请人 |
VERTEX PHARMACEUTICALS INCORPORATED;TERMIN, ANDREAS;WILSON, DEAN;JOSHI, PRAMOD |
发明人 |
TERMIN, ANDREAS;WILSON, DEAN;JOSHI, PRAMOD |
分类号 |
C07D401/04;A61K31/47;A61K31/496;C07D295/14 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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