发明名称 Treatment of statin side effects
摘要 Disclosed are combinations of uridine and biological precursors of uridine and compounds of formula (I) wherein R1 is selected from H or alkyl; R2 and R3 are each independently selected from H, OH, alkyl, alkoxy, alkenyl, alkenoxy or alkynoxy; and R4 is alkyl, alkenyl, alkoxy, alkenoxy, alkylol or alkenylol. A preferred compound of formula (I) is Coenzyme Q10. Combinations as described above are useful in the treatment of the side effects of statin therapy, in particular muscle pain. Also disclosed is the use of said combinations for the treatment of muscle pain or fatigue not related to the use of statins.
申请公布号 NZ526069(A) 申请公布日期 2006.11.30
申请号 NZ20010526069 申请日期 2001.11.29
申请人 MAGRAL LIMITED 发明人 LINNANE, ANTHONY WILLIAM
分类号 A61K47/00;A61K31/122;A61K31/137;A61K31/22;A61K31/366;A61K31/40;A61K31/404;A61K31/4418;A61K31/505;A61K31/7072;A61K45/00;A61K45/06;A61P3/06;A61P5/38;A61P9/10;A61P11/14;A61P19/02;A61P21/00;A61P25/02;A61P25/20;A61P27/16;A61P29/00;A61P35/00;A61P43/00;(IPC1-7):A61K31/122;A61K31/707 主分类号 A61K47/00
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