N[S(4-aryl-triazol-3-yl)alpha-mercaptoacetyl]-p-amino benzoic acids as HIV reverse transcriptase inhibitors

摘要

A series of S-triazolyl alpha-mercaptoacetanilides having N-(alpha-mercaptoacetyl) p amino benzoic acid derivatives. are provided, where Q is CO₂H, or a salt or ester thereof, or a C(O)N-linked amino acid. The compounds inhibit several variants of the reverse transcriptase of HIV, and are useful in the treatment of HIV infections.