| 摘要 |
<p>The invention relates to compounds with formula I and II : wherein R, R1, R2, R3 and A have the meanings given in the description and have selective A3 adenosine receptor agonist activity. These compounds can be used in a pharmaceutical composition to treat disorders caused by excessive activation of A3 receptor, or can be used in diagnostic application to determine the relative binding of other compounds to the A3 receptor. The compounds can be labeled, for example, with fluorescent or radiolabels, and the labels can be used for in vivo or in vitro determination of the presence of tumor cells which passes a high concentration of adenosine A3 receptors.</p> |
