摘要 |
<p>Powder for making bioabsorbable calcium phosphate cements has a defined particle size distribution, comprises 65-99.9 wt.% orthophosphates and 0.1-35 wt.% diphosphates, and comprises 35-99.9 wt.% of a primary crystal phase consisting of calcium sodium and/or potassium orthophosphates, 0.1-20 wt.% of a secondary crystal phase consisting of sodium and/or potassium polyphosphates, and 0.1-65 wt.% of an amorphous phase. Powder for making bioabsorbable calcium phosphate cements comprises 40-99 vol.% of 0.1-10 mum particles, 1-20 vol.% of 10-43 mum particles and 0-59 vol.% of 43-315 mum particles, comprises 65-99.9 wt.% orthophosphates and 0.1-35 wt.% diphosphates, and comprises 35-99.9 wt.% of a primary crystal phase consisting of calcium sodium and/or potassium orthophosphates of formula (I) and/or (II), 0.1-20 wt.% of a secondary crystal phase consisting of sodium and/or potassium polyphosphates, and 0.1-65 wt.% of an amorphous phase. Ca2K1-xNa1+x(PO4)2 (I) Ca10KyNa1-y(PO4)7 (II) x = 0.1-0.9; y = 0-1. An Independent claim is also included for a biodegradable implant with open or closed porosity made from a powder as above in the form of an aqueous solution, suspension or paste that has been hardened ex vivo.</p> |