PYRIDINE [3 , 4-B] PYRAZINONE COMPOUNDS AS PDE-5 INHIBITORS

摘要

Compounds, tautomers of the compounds, and pharmaceutically acceptable salts of the compounds or tautomers are disclosed, wherein the compounds have the structure of Formula (I), wherein R2<SUP>2</SUP>, X<SUP>6</SUP>, Y<SUP>6</SUP>, R<SUP>6</SUP>, and R<SUP>8</SUP> are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, synthetic methods, and intermediates are also disclosed.