VECTORIZATION OF dsRNA BY CATIONIC PARTICLE AND TOPICAL USE

摘要

PROBLEM TO BE SOLVED: To provide vectorization of dsRNA by a cationic particle and a topical use. SOLUTION: The topical composition for the skin, mucosa and eyes comprises the association of at least one dsRNA and at least one cationic particle in vectorization of dsRNA oligonucleotide by a cationic particle selected from a surfactant micelle, a block or non-block polymer micelle, a cationic liposome and a niosome, a cationic oleosome, a cationic nanoemulsion, a cationic organic or inorganic particle and a nanocapsule. COPYRIGHT: (C)2007,JPO&INPIT