发明名称 |
Synergism of photodynamic and electropermeation effects on cell vitality as a novel cytotoxic agent |
摘要 |
The present invention is based on the discovery that electroporation of a photosensitive agent in a cell and subsequent activation of the agent provides more effective killing of the electroporated cell than cells exposed to a photosensitive agent alone. The invention provides a method and apparatus for inhibiting cell growth or enhancing cell death. The method includes providing a photosensitive agent to a cell; applying an electric pulse to the cell of a sufficient strength and duration to electroporate the cell with the photosensitive agent; and applying light of an activatable wavelength to the cell thereby activating the agent and inhibiting cell growth or enhancing cell death.
|
申请公布号 |
US2006270967(A1) |
申请公布日期 |
2006.11.30 |
申请号 |
US20060450736 |
申请日期 |
2006.06.08 |
申请人 |
BERG HERMAN;LAMBREYA MAYA |
发明人 |
BERG HERMAN;LAMBREYA MAYA |
分类号 |
A61N1/30;A61K41/00;A61N1/32;A61N5/06 |
主分类号 |
A61N1/30 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|