摘要 |
The invention concerns novel peptides exhibiting antimicrobial properties, polypeptides comprising said peptides, methods for preparing same, polynucleotides coding for said peptides, chimeric genes, vectors containing said polynucleotides or said chimeric genes and transformed organisms. The novel inventive peptides are peptides of formula (1): C-x(3,7)-C-x(2,4)-C-x(9,10)-C-x(3,6)-CC wherein x(3,7), x(2,4), x(9,10) and x(3,6), do not have the same values at the same time forming the peptide sequences defined by the following five formulae: (1A), (1B), (1C), (1D), and (1E): (1A): C-x(2)-x-x(1,5)-C-[RKQET]-x(2,3)-C-x(3)-[EDNL]-x(5,6)-C-x(3,6)-CC (1B): C-x(3)-G-x(2)-C-x(3,4)-C-x(9,10)-C-x(2,5)-KCC (1C): C-x(4)-G-x-C-x(3,4)-C-x(7,8)-[ASG]-[TSNHKL]-C-x(5,6)-CC (1D): C-[LVIF]-[QE]-x(4)-C-x(3,4)-C-x(9,10)-C-Y-x(2)-[KR]-G-x-CC (1E): C-M-x(2)-G-x(2)-CWGPC-x(9)-C-x(6)-CC. |
申请人 |
UNIVERSITE DE RENNES 1;INNOVA PROTEOMICS;INRIA;JEGOU, BERNARD;PINEAU, CHARLES;BOURGEON, FREDERIC;NICOLAS, JACQUES;BASTIDE, YVES;MESCAM, YOANN |
发明人 |
JEGOU, BERNARD;PINEAU, CHARLES;BOURGEON, FREDERIC;NICOLAS, JACQUES;BASTIDE, YVES;MESCAM, YOANN |