摘要 |
(I) (wherein R1 and R2 each represents hydrogen, C1-8 alkyl, etc.; R 3 represents either C1-8 alkyl optionally substituted by one to three halogen atoms or phenyl; R4 represents hydrogen, etc.; R5 and R6 each represents hydrogen, C1-8 alkyl, etc.; X represents sulfur, oxygen, etc.; and ring A represents an optionally substituted cyclic group) or a salt thereof. The compound represented by the general formula (I) is extremely lowly toxic and is hence useful as a safe medical product. It has PPARdelta agonistic activity and is hence useful as a preventive and/or therapeutic agent for diseases caused by sugar/lipid abnormal metabolism, hypertension, circulatory diseases, etc.
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