| 发明名称 |
Diaryl ethers as opioid receptor antagonist |
| 摘要 |
A compound of the formula (I)
wherein the variables X 1 to X 10 , R 1 to R 7 including R 3' , E, v, y, z, A and B are as described, or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obesity and Related Diseases is disclosed. |
| 申请公布号 |
ZA200502276(B) |
申请公布日期 |
2006.11.29 |
| 申请号 |
ZA20050002276 |
申请日期 |
2005.03.17 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
BLANCO-PILLADO, MARIA-JESUS;DE LA TORRE, MARTA GARCIA;FRITZ, JAMES ERWIN;MATT, JR., JAMES EDWARD;PEDREGAL-TERCERO, CONCEPCION;SIEGEL, MILES GOODMAN;STUCKY, RUSSELL DEAN;THOMAS, ELIZABETH MARIE;CHAPPELL, MARK DONALD;DIAZ BUEZO, NURIA;HOLLOWAY, WILLIAM GLEN;MITCH, CHARLES HOWARD;QUIMBY, STEVEN JAMES;SMITH, DANA RAE;TAKEUCHI, KUMIKO;WOLFE, CHAD NOLAN |
| 分类号 |
A61K;A61P;A61P3/04;C07C;C07C235/46;C07D;C07D213/38;C07D213/64;C07D213/643;C07D213/78;C07D213/81;C07D213/82;C07D217/04;C07D237/24;C07D241/24;C07D307/14;C07D333/20;C07D401/06;C07D401/12;C07D401/14;C07D405/12;C07D409/12;C07D409/14;C07D413/12;C07D417/12;C07D417/14 |
主分类号 |
A61K |
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