发明名称 Biphenyl derivatives
摘要 This invention provides biphenyl derivatives of formula I: wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>7</SUP>, W, a, b and c are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The biphenyl derivatives of this invention possess both beta<SUB>2 </SUB>adrenergic receptor agonist and muscarinic receptor antagonist activity and therefore, such biphenyl derivatives are useful for treating pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.
申请公布号 US7141671(B2) 申请公布日期 2006.11.28
申请号 US20040779157 申请日期 2004.02.13
申请人 THERAVANCE, INC. 发明人 MAMMEN MATHAI;DUNHAM SARAH;HUGHES ADAM;LEE TAE WEON;HUSFELD CRAIG;STANGELAND ERIC;CHEN YAN
分类号 C07D211/56;A61K31/445;A61K31/452;A61K31/47;A61K31/4709;C07D211/46;C07D211/48;C07D211/58;C07D211/72;C07D401/06;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D409/06;C07D409/12;C07D409/14;C07D453/02;C07D471/08;G01N33/94 主分类号 C07D211/56
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