| 发明名称 |
CONDENSED PYRAMIDINE COMPOUNDS AS INHIBITORS OF VOLTAGE-GATED ION CHANNELS |
| 摘要 |
The present invention relates to compounds of formula (I) useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. Wherein R1, R2, X1-X4, P, and ring A are as defined in the present application.
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| 申请公布号 |
KR20060118398(A) |
申请公布日期 |
2006.11.23 |
| 申请号 |
KR20067002458 |
申请日期 |
2006.02.03 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED;ZHANG YULIAN;MARTINBOROUGH, ESTHER;WANG JIAN;ZIMMERMAN NICOLE;GONZALES JESUS E. III |
发明人 |
WILSON DEAN M.;TERMIN ANDREAS P.;NEUBERT TIMOTHY D. |
| 分类号 |
C07D239/94;A61K31/517;A61K31/5377;A61P25/00;A61P29/00;C07D239/70;C07D239/91;C07D401/04;C07D401/14;C07D403/04;C07D405/12;C07D413/02;C07D471/04;C07D495/04 |
主分类号 |
C07D239/94 |
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