发明名称 Pyridomorphinans, thienomorphinans and use thereof
摘要 Compounds represented by the formulae: wherein each of Y, X and R individually is selected from the group consisting of hydrogen, hydroxy, halo, CF<SUB>3</SUB>, NO<SUB>2</SUB>, CN, NH<SUB>2</SUB>, COR<SUP>1 </SUP>and CO<SUB>2</SUB>R<SUP>2 </SUP>wherein R<SUP>1 </SUP>is selected from the group consisting of alkyl, aryl, alkaryl, and NH<SUB>2</SUB>, and R<SUP>2 </SUP>is selected from the group consisting of alkyl, aryl and aralkyl, and provided that at least one of Y, X and R is other than H; and pharmaceutically acceptable salts thereof are provided. Compounds of the above formula are useful as analgesics for treating pain, as immunomodulators and for treating drug abuse.
申请公布号 US2006264452(A1) 申请公布日期 2006.11.23
申请号 US20060492095 申请日期 2006.07.25
申请人 SOUTHERN RESEARCH INSTITUTE 发明人 ANANTHAN SUBRAMANIAM
分类号 A61K31/485;C07D489/09;A61P25/04;A61P25/30;A61P25/36;A61P37/02;A61P37/04;A61P43/00;C07D489/12;C07D491/20;C07D495/18;C07D495/20 主分类号 A61K31/485
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