SUBSTRATE FUNCTIONALIZATION METHOD FOR HIGH SENSITIVITY APPLICATIONS
摘要
A method for functionalizing substrates such as magnetic beads and glass slides is provided. The method involves providing substrate surfaces with activated polyacrylic acid (PAA) and attaching one or more desired capture probes. Substrates prepared by the method are particularly useful in ultrasensitive detection assays as they exhibit very low specific binding and high binding efficiency relative to conventional substrates.
申请公布号
WO2006125124(A2)
申请公布日期
2006.11.23
申请号
WO2006US19339
申请日期
2006.05.18
申请人
NANOSPHERE, INC.;MARLA, SUDHAKAR, S.;BAO, YIJIA, PAUL;HUBER, MARTIN
发明人
MARLA, SUDHAKAR, S.;BAO, YIJIA, PAUL;HUBER, MARTIN