ANTI-MESOTHELIN ANTIBODIES USEFUL FOR IMMUNOLOGICAL ASSAYS
摘要
The present invention provides antibodies that have a surprisingly good combination of affinity for mesothelin and ability to be used in immunological assays for detecting the presence of mesothelin in biological samples. The invention further provides methods of using the antibodies, and kits comprising them. The antibodies can also be used to target toxins and other agents to cells expressing mesothelin, and can be used in methods and medicaments for inhibiting the growth of such cells.
申请公布号
WO2006124641(A2)
申请公布日期
2006.11.23
申请号
WO2006US18502
申请日期
2006.05.11
申请人
THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH;PASTAN, IRA, H.;ONDA, MASANORI