CANCER TREATMENT BY COMBINED INHIBITION OF TELOMERASE AND HSP90 ACTIVITIES
摘要
<p>A method and kit for inhibiting the proliferation of cancer cells are disclosed, based on a combination of an HSP90 inhibitor and a telomerase inhibitor. When used in cancer therapy, the two compounds in combination enhance the anti-cancer treatment efficacy obtained with the HSP90 inhibitor alone or the telomerase inhibitor alone. Preferably, efficacy is supraadditive or synergistic in nature relative to the combined effects of the individual agents, with minimal exacerbation of side effects.</p>
申请公布号
WO2006124904(A2)
申请公布日期
2006.11.23
申请号
WO2006US18927
申请日期
2006.05.16
申请人
GERON CORPORATION;DANA-FARBER CANCER INSTITUTE;MUNSHI, NIKHIL, C.;SHAMMAS, MASOOD, A.;GRYAZNOV, SERGEI
发明人
MUNSHI, NIKHIL, C.;SHAMMAS, MASOOD, A.;GRYAZNOV, SERGEI