发明名称 |
NANOPARTICULATE AND CONTROLLED RELEASE COMPOSITIONS COMPRISING A PLATELET AGGREGATION INHIBITOR |
摘要 |
The present invention provides a composition comprising a platelet aggregati on inhibitor, for example, cilostazol, or a salt or derivative thereof, useful in the treatment and prevention of ischemic symptoms. The invention provides a composition which comprises nanoparticulate particles comprising the platelet aggregation inhibitor and at least one surface stabilizer. The nanoparticulate particles have an effective average particle size of less than about 2000 nm. The invention provides also a composition that delivers a platelet aggregation inhibitor, or nanoparticles comprising the same, in a pulsatile or continuous manner.
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申请公布号 |
CA2611506(A1) |
申请公布日期 |
2006.11.23 |
申请号 |
CA20062611506 |
申请日期 |
2006.05.23 |
申请人 |
ELAN PHARMA INTERNATIONAL LIMITED |
发明人 |
JENKINS, SCOTT;LIVERSIDGE, GARY;STARK, PAUL;REKHI, GURVINDER SINGH;FANNING, NIALL;DEVANE, JOHN G. |
分类号 |
A61K31/4709;A61K9/00;A61K9/14;A61K9/20;A61K9/51;A61K9/54;A61P9/10 |
主分类号 |
A61K31/4709 |
代理机构 |
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代理人 |
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主权项 |
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