| 发明名称 |
Therapeutic and diagnostic cloned MHC-unrestricted receptor specific for the MUC1 tumor associated antigen |
| 摘要 |
The invention provides an isolated nucleic acid encoding a receptor, other than an immunoglobulin, wherein the receptor binds to a MUC1 tumor antigen independently of an major histocompatibility complex (MHC). The invention provides a method of activating a signaling pathway and/or killing a cancer cell using a receptor that is similar to or is a T cell receptor
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| 申请公布号 |
US2006263334(A1) |
申请公布日期 |
2006.11.23 |
| 申请号 |
US20050295767 |
申请日期 |
2005.12.07 |
| 申请人 |
UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |
发明人 |
FINN OLIVERA J.;ALAJEZ NEHAD M.;SCHMIELAU JAN;ALTER MARK D. |
| 分类号 |
G01N33/53;A61K48/00;C07H21/04;C07K14/705;C07K16/28;C12N15/867;C12P21/06 |
主分类号 |
G01N33/53 |
| 代理机构 |
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