发明名称 |
Tumor associated antigen, peptides thereof, and use of same as anti-tumor vaccines |
摘要 |
The invention relates to colon and prostate tumor associated antigen peptides obtainable from prostate specific G protein-coupled receptor (PSGR), six-transmembrane epithelial antigen of prostate (STEAP) and proteins encoded by genes found overexpressed in colon carcinoma cells, such as human 1-8D interferon induced transmembrane protein 2. The invention further relates to a polynucleotide encoding the tumor associated antigen peptides and to pharmaceutical compositions, which are preferably anti-tumor vaccine compositions, containing a tumor associated antigen, at least one tumor associated antigen peptide thereof, or encoding polynucleotide thereof as an active ingredient. The pharmaceutical compositions can be administered to a patient in need thereof to treat or inhibit the development of colon or prostate cancer.
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申请公布号 |
US2006263342(A1) |
申请公布日期 |
2006.11.23 |
申请号 |
US20050524787 |
申请日期 |
2005.09.23 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD. |
发明人 |
EISENBACH LEA;TIROSH BOAZ;CARMON LIOR;MACHLENKIN ARTHUR;PAZ ADRIAN;TZEHOVAL ESTHER;FRIDKIN MATITYAHU |
分类号 |
A61K48/00;A61K38/00;A61K39/00;C07K14/47;C07K14/705;C07K14/72;C07K14/82;C12N5/08 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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