| 发明名称 |
Dyrks as modifiersof the apc and axin pathways and methods of use |
| 摘要 |
Human DYRK genes are identified as modulators of the APC and Axin pathways, and thus are therapeutic targets for disorders associated with defective APC and Axin function. Methods for identifying modulators of APC and Axin, comprising screening for agents that modulate the activity of DYRK are provided.
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| 申请公布号 |
US2006265763(A1) |
申请公布日期 |
2006.11.23 |
| 申请号 |
US20040545193 |
申请日期 |
2004.02.10 |
| 申请人 |
EXELIXIS, INC. |
发明人 |
GENDREAU STEVEN B.;MORABLANCO EVA L.;HAUER TIMOTHY S.;LICKTEIG KIM |
| 分类号 |
A01K67/027;A61K31/7088;A61K39/395;A61K45/00;A61K48/00;A61P35/00;C12N;C12N1/00;C12N15/00;C12Q1/00;C12Q1/02;C12Q1/48;C12Q1/68;G01N33/573;G01N33/574 |
主分类号 |
A01K67/027 |
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