发明名称 A SPORADIC TUMOR MOUSE MODEL FOR DRUG DISCOVERY
摘要 The present invention relates to a transgenic mouse containing a latent oncogenic ß-catenin allele capable of spontaneous activation in vivo. The transgenic mouse is useful for the identification of compounds and immunotherapies for the prevention, treatment and/or cure of various forms of cancer associated with ß-catenin activation.
申请公布号 WO2006099037(A3) 申请公布日期 2006.11.23
申请号 WO2006US08398 申请日期 2006.03.09
申请人 SCHERING CORPORATION;COSTE-INVERNIZZI, ISABELLE;RENNO, TOUFIC 发明人 COSTE-INVERNIZZI, ISABELLE;RENNO, TOUFIC
分类号 C12N15/85;A01K67/027;A61K49/00;C07K14/47 主分类号 C12N15/85
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