摘要 |
The present invention provides compounds represented by Formula I. R<SUB>0 </SUB>is selected from hydrogen, halogen, lower alkyl, -SR<SUP>8</SUP>, -OR<SUP>8</SUP>, -CN, and -NHR<SUP>8</SUP>, R<SUB>1 </SUB>is halogen, or lower alkyl; R<SUB>2 </SUB>is -NHR<SUP>8</SUP>; R<SUB>3 </SUB>is selected from the group consisting of hydrogen, halogen, -SR<SUP>8</SUP>, -OR<SUP>8</SUP>, -CN, -C(O)R<SUP>9</SUP>, -C(O)OH, -NO<SUB>2</SUB>, -NR<SUP>8</SUP>R<SUP>10</SUP>, lower alkyl, lower alkenyl, lower alkynyl, lower perhaloalkyl, aryl, heteroaryl, alicyclic and heterocyclic, all optionally substituted, and R<SUB>5 </SUB>is aryl, heteroaryl, alicyclic, or heterocyclic:
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