发明名称 |
4-aminopyrimidine derivatives |
摘要 |
This invention is 4-aminopyrimidine derivatives of the formula wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3 </SUP>and R<SUP>4 </SUP>are as defined in the specification or a pharmaceutically acceptable salt thereof. The invention also is the preparation of compounds of formula I, pharmaceutical compositions containing therapeutically effective amounts of compounds of formula I or pharmaceutically acceptable salts thereof and to a method of treatment comprising administering therapeutically effective amounts of the compound of formula I for the prevention or treatment of mGluR5 receptor mediated disorders.
|
申请公布号 |
US7138404(B2) |
申请公布日期 |
2006.11.21 |
申请号 |
US20020135150 |
申请日期 |
2002.04.29 |
申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
MUTEL VINCENT;PETERS JENS-UWE;WICHMANN JUERGEN |
分类号 |
A61K31/513;C07D239/47;A61K31/505;A61K31/506;A61P1/00;A61P1/16;A61P3/10;A61P9/10;A61P13/02;A61P13/12;A61P19/02;A61P19/06;A61P21/00;A61P21/02;A61P25/00;A61P25/04;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/34;A61P25/36;A61P27/02;A61P29/00;A61P29/02;A61P31/18;A61P35/00;A61P43/00;C07D239/46;C07D403/06;C07D405/06;C07D409/06;C07D413/06;C07D413/12;C07D413/14 |
主分类号 |
A61K31/513 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|