发明名称 |
Antibodies that immunospecifically bind BLyS |
摘要 |
The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.
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申请公布号 |
US7138501(B2) |
申请公布日期 |
2006.11.21 |
申请号 |
US20010880748 |
申请日期 |
2001.06.15 |
申请人 |
HUMAN GENOME SCIENCES, INC. |
发明人 |
RUBEN STEVEN M.;CHOI GIL H.;VAUGHAN TRISTAN;HILBERT DAVID |
分类号 |
C07K16/00;G01N33/53;A61K45/00;A61K47/48;A61K49/00;A61P35/00;A61P37/00;A61P37/04;A61P37/06;C07K14/52;C07K14/705;C07K16/18;C07K16/28;C07K16/46;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/08;G01N33/564 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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