INTRANASAL ADMINISTRATION OF ACTIVE AGENTS TO THE CENTRAL NERVOUS SYSTEM
摘要
A method for delivering a polypeptide to the central nervous system of a mammal is provided. The method involves attaching the polypeptide to an antibody or an antibody fragment and administering the fusion polypeptide intranasally, for delivery to the central nervous system. Methods of treatment are also provided, where a therapeutically effective amount of the composition is delivered to the nasal cavity of a mammal.
申请公布号
WO2006091332(A3)
申请公布日期
2006.11.16
申请号
WO2006US03110
申请日期
2006.01.27
申请人
ALZA CORPORATION;BENTZ, HANNE;HILL, BETH;LUCAS, CATHERINE;FREY, WILLIAM, H.
发明人
BENTZ, HANNE;HILL, BETH;LUCAS, CATHERINE;FREY, WILLIAM, H.