GLUCAGON-LIKE PEPTIDE 1 (GLP-1) RECEPTOR AGONISTS AND THEIR PHARMACOLOGICAL METHODS OF USE
摘要
This invention provides peptides with novel modifications that provide suitable derivatization sites to improve the pharmacokinetic properties of the peptides. These GLP-1 modified peptides function in vivo as agonists of the GLP-1 receptor. The peptides of the present invention provide a new therapy for patients with decreased endogenous insulin secretion, for example, type 2 diabetics.
申请公布号
WO2006121860(A2)
申请公布日期
2006.11.16
申请号
WO2006US17411
申请日期
2006.05.05
申请人
BAYER PHARMACEUTICALS CORPORATION;WHELAN, JAMES;LUMB, KEVIN;CLAIRMONT, KEVIN