| 摘要 |
<p>Device for slow liberation via transdermic process of a medicine for excess of cholesterol and method of production of a transdermic device, which is characterized for contemplating a bi-laminate device for slow transdermic liberation comprising a flexible macromolecular matrix (2) of thickness 0,15 to 0,6 cm and the surface from 10 to 100 square cm and presents a posterior coating (1) on one side which allows a considerable reduction (more than 15 times) of the doses to be administered in the treatment for excess of cholesterol; the macromolecular matrix contains and liberates in a continuous way for a period between 1 to 4 months from 0,05 to 0,18% a day of its total weight in Omega 3 and/or statin by its surface in contact with the patient's skin without being necessary the device to be adhered in a fix and permanent way to the his/her skin, which is characterized for contemplating a bi-laminate device for slow transdermic liberation comprising a flexible macromolecular matrix (2) of thickness 0,15 to 0,6 cm and the surface from 10 to 100 square cm and presents a posterior coating (1) on one side which allows a considerable reduction (more than 15 times) of the doses to be administered in the treatment for excess of cholesterol; the macromolecular matrix contains and liberates in a continuous way for a period between 1 to 4 months from 0,05 to 0,18% a day of its total weight in Omega 3 and/or statin by its surface in contact with the patient's skin without being necessary the device to be adhered in a fix and permanent way to the his/her skin.</p> |
