摘要 |
<p>[PROBLEMS] To provide a compound which can be used as a therapeutic agent for a disease in which an EP1 receptor is involved, particularly a lower urinary tract disease such as pollakiuria/urinary urgency and incontinence associated with overactive bladder, cystitis, interstitial cystitis and prostatitis. [MEANS FOR SOLVING PROBLEMS] It is found that a bicyclic heterocyclic derivative in which benzene rings are fused or a salt thereof has a potent EP1 receptor-antagonistic effect. The bicyclic heterocyclic derivative or salt thereof can be used as a therapeutic agent for a disease in which an EP1 receptor is involved, particularly a lower urinary tract disease such as pollakiuria/urinary urgency and incontinence associated with overactive bladder, cystitis, interstitial cystitis and prostatitis.</p> |
申请人 |
HIRANO, YUSUKE;WATANABE, TORU;ASTELLAS PHARMA INC.;KUBOTA, HIDEKI;TSUKAMOTO, ISSEI;SUZUKI, DAISUKE;KOSHIO, HIROYUKI;KAMIJO, KAZUNORI;OHNUKI, KEI;KATO, KOJI;FUKUDA, YUTA |
发明人 |
KUBOTA, HIDEKI;TSUKAMOTO, ISSEI;SUZUKI, DAISUKE;KOSHIO, HIROYUKI;KAMIJO, KAZUNORI;OHNUKI, KEI;KATO, KOJI;FUKUDA, YUTA;HIRANO, YUSUKE;WATANABE, TORU |