| 摘要 |
A drug-formulating method, a drug commercial-distribution method, and a drug formulation improve safety of a drug that is at risk for abuse-such as methylphenidate, or amphetamine, or an amphetamine-like central-nervous-system stimulant. The drug is formulated into a form (not a transdermal patch) that tends to deter conversion to powder; and in this form commercially distributed, e. g. wholesale or retail. Preferably that form is enclosed in a nontoxic capsule. Preferably the formulating includes dissolving or dispersing the drug into or onto a nontoxic carrier-for example a gel, e. g., methylcellulose, hydroxymethylcellulose, carbomer polymer, or other gelatinous pharmaceutical agent that is FDA-acceptable. Preferably the carrier is water-insoluble, to deter dissolving in water for injection. The carrier may be an oil or a solid-for example paper or other thin medium broadly extended in two dimensions, or a sponge or other medium having generally coarse cellular structure.
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