METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO ALCOHOL

摘要

PROBLEM TO BE SOLVED: To provide a method for efficiently producing an optically active β-amino alcohol useful as medicines, agrochemicals or their synthetic intermediates from an α-aminoketone.

SOLUTION: An optically active β-amino alcohol expressed by general formula (IV) is produced by reducing an α-aminoketone expressed by general formula (I) in the presence of a group VIII metal compound expressed by general formula (II), an optically active diamine expressed by general formula (III) and a hydrogen donor.

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