发明名称 |
TRITERPENE HYDROXYLASE |
摘要 |
Soyasapogenol B is biosynthesized via two steps of hydroxylation reaction of its precursor ²-amyrin. However, the gene of the hydroxylase concerned in this reaction has not been revealed. Therefore, it was impossible to apply a genetic engineering technique on the hydroxylase. The present inventors reveals that a sequence which corresponds to a soybean-derived cytochrome P-450 gene CYP93E1 encodes an enzyme protein that carries out hydroxylation of the 24-position of an oleanane type triterpene, and also provides a method for applying said gene making use of a genetic engineering technique. |
申请公布号 |
EP1721983(A1) |
申请公布日期 |
2006.11.15 |
申请号 |
EP20050719556 |
申请日期 |
2005.02.25 |
申请人 |
MEIJI SEIKA KAISHA, LTD. |
发明人 |
HAYASHI, HIROAKI;INOUE, KENICHIRO;HOSHINO, MASATERU;SHIBUYA MASAAKI;EBIZUKA YUTAKA |
分类号 |
C12N15/53;C12N1/19;C12N9/00;C12N9/02;C12P15/00;C12P33/06;C12R1/645;C12R1/91 |
主分类号 |
C12N15/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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