发明名称 Linear chain substituted monocyclic and bicyclic derivatives as factor Xa inhibitors
摘要 The present application describes linear chain substituted monocyclic and bicyclic compounds and derivatives thereof of Formula I: <?in-line-formulae description="In-line Formulae" end="lead"?>P<SUB>4</SUB>-P-M-M<SUB>4</SUB>I<?in-line-formulae description="In-line Formulae" end="tail"?> or pharmaceutically acceptable salt forms thereof, P-M are rings substituted by a linear group. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
申请公布号 US7135469(B2) 申请公布日期 2006.11.14
申请号 US20040801519 申请日期 2004.03.16
申请人 BRISTOL MYERS SQUIBB, CO. 发明人 PINTO DONALD J.
分类号 A61K31/5377;A61K31/437;A61K31/497;C07D;C07D413/02;C07D471/02;C07D471/06 主分类号 A61K31/5377
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