发明名称 |
Intraluminar perforated radially expandable drug delivery prosthesis and a method for the production thereof |
摘要 |
The radially expandable prosthesis for implantation in a lumen comprises a tubular wall produced from sheet metal and showing cuts enabling the prosthesis to expand. By using water guided laser cutting technology to make these cuts and/or specific electrochemical polishing technology a more biocompatible prosthesis is obtained, causing less thrombogenicity and less foreign body reaction. By covering an intraluminal prosthesis with a titaniumnitride coating the biocompatibility of the prosthesis is improved. By applying perforating or non-perforating holes ( 4 ) and filling these holes with a therapeutic agent, the intraluminal prosthesis can be used to locally administer medicines, genes and or other substances to prevent in this way thrombotic occlusions and/or neointimal hyperplasia and prosthesis narrowing. Using this specific perforated prosthesis design the total drug capacity can be increased and also the drug release time prolongs significantly.
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申请公布号 |
US7135039(B2) |
申请公布日期 |
2006.11.14 |
申请号 |
US20010798990 |
申请日期 |
2001.03.06 |
申请人 |
BOSTON SCIENTIFIC SCIMED, INC. |
发明人 |
DE SCHEERDER IVAN;SOHIER JUERGEN;VAN DER LEDEN NATASJA;VAN HUMBEECK JAN |
分类号 |
A61F2/06;A61F2/00;A61F2/90;A61F2/91;A61F2/915 |
主分类号 |
A61F2/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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