发明名称 |
Compositions and methods for eliciting an immune response to gram-negative bacterial infections |
摘要 |
Compositions for eliciting an immune response against Gram-negative bacterial infections and methods of making such compositions are provided. The composition comprises glycosylated pilin, the pilin being glycosylated with the O-antigen of a target Gram-negative bacteria of interest. Methods of eliciting an immune response by administration of such compositions are also provided.
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申请公布号 |
US7135175(B2) |
申请公布日期 |
2006.11.14 |
申请号 |
US20050192962 |
申请日期 |
2005.07.29 |
申请人 |
DUQUESNE UNIVERSITY OF THE HOLY GHOST |
发明人 |
CASTRIC PAUL A. |
分类号 |
A61K39/00;C12N15/09;A61K39/02;A61K39/07;A61K39/108;A61K39/38;A61K39/395;A61P31/04;C07K1/02;C07K14/195;C07K14/21;C07K14/435;C07K14/77;C12P19/26;C12P21/02;C12P21/08;C12Q1/04;C12R1/385 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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