| 摘要 |
FIELD: organic chemistry, medicinal biochemistry, medicine, pharmacy. ^ SUBSTANCE: invention relates to compounds of the formula (I): wherein R1, R2, R3, R4, R5 and R6 mean independently of one another (C0-C30)-alkaline-(LAG) and wherein one or more C-atoms of alkylene group can be substituted with -O-, -(C=O)-, -N-((C1-C6)-alkyl)-, -N-((C1-C6)-alkylphenyl)- or -NH-; H, F, Cl, Br, and J atoms, -O-(C1-C6)-alkyl, -NH2; (LAG) means residue of acyclic monosugar, trialkylammonium alkyl residue or -O-(SO2)-OH wherein at least one of residues R1-R6 can has value (C0-C30)-alkylene-(LAG) wherein one or more C-atoms of alkylene residue can be substituted with -O-, -(C=O)-, -N-((C1-C6)-alkyl)-, -N-((C1-C6)-alkylphenol)- or -NH- and wherein residues R1 and r2 must not have values -O-sugar residue, and to their pharmaceutically acceptable salts. Indicated compounds possess the therapeutically useful hypolipidemic effect, differ by insignificant resorption and can be used for using as medicines in treatment of lipid metabolism disorders, such as hyperlipidemia, decreasing level of serum blood cholesterol, treatment of arteriosclerotic symptoms and insulin resistance. ^ EFFECT: valuable medicinal properties of substances, agents, improved preparing method. ^ 12 cl, 12 ex |
