发明名称 |
Lectin conjugates |
摘要 |
A conjugate includes at least one target-seeking unit, which specifically binds to receptors on the surface of endothelial cells, and at least one effector unit which is coupled to the unit by a linker. The effector unit exhibits at least one signal unit and optionally at least one therapeutic active substance. The target-seeking unit includes a lectin or a fragment or derivative thereof, wherein the lectin is not L-selectin and the signal unit includes a lanthanide ion.
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申请公布号 |
US2006251580(A1) |
申请公布日期 |
2006.11.09 |
申请号 |
US20050294963 |
申请日期 |
2005.12.06 |
申请人 |
FAUSTUS FORSCHUNGS CIE.TRANSLATIONAL CANCER RESEARCH GMBH |
发明人 |
KEPPLER BERNHARD;DEBBAGE PAUL;BUCHBERGER WOLFGANG |
分类号 |
A61K51/00;A61K45/00;A61K47/48;A61K49/06;A61K49/10;A61K49/14;A61K49/18;A61K51/08;C07K;C07K2/00;C07K14/47;C07K16/46 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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