发明名称 Antibodies to TGF-beta
摘要 The present invention relates to antibody molecules, in particular antibody molecules that bind Transforming Growth Factor beta (TGFbeta), and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralise TGFbeta1, TGFbeta2 and TGFbeta3, so-called "pan-specific" antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).
申请公布号 US2006251658(A1) 申请公布日期 2006.11.09
申请号 US20060350906 申请日期 2006.02.08
申请人 LEDBETTER STEVEN R;HART CELIA P;HOLGATE ROBERT G;JERMUTUS LUTZ U;BUCHANAN CATRIONA L;DUNCAN ALEXANDER R;FINCH DONNA K 发明人 LEDBETTER STEVEN R.;HART CELIA P.;HOLGATE ROBERT G.;JERMUTUS LUTZ U.;BUCHANAN CATRIONA L.;DUNCAN ALEXANDER R.;FINCH DONNA K.
分类号 A61K39/395;C07H21/04;C07K16/22;C12N5/06;C12P21/06 主分类号 A61K39/395
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