Transmucosal drug delivery systems comprise an inert core and a coating layer comprising at least one active agent, at least one bioadhesive substance, at least one plasticizer, and optionally one or more pharmaceutically acceptable excipients. The transmucosal drug delivery systems are designed to remain localized on mucosal surfaces while providing high surface area for rapid release of the pharmaceutically active agent or rapid release of a fraction of the pharmaceutically active agent followed by sustained delivery.
