The addition of buffer to a harvest stream during diafiltration can cause increased turbidity and have other undesirable effects including limiting product recovery. Methods and compositions related to the use of a non-ionic surfactant are provided for improving diafiltration.
申请公布号
WO2006087643(A3)
申请公布日期
2006.11.09
申请号
WO2006IB01231
申请日期
2006.01.24
申请人
WYETH RESEARCH IRELAND LIMITED;PIERCE, JAMES;MORAN, ENDA