发明名称 |
COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE |
摘要 |
The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: Formula (I) wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, I, m and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia. |
申请公布号 |
WO2006117686(A2) |
申请公布日期 |
2006.11.09 |
申请号 |
WO2006IB01587 |
申请日期 |
2006.02.23 |
申请人 |
THE GOVERNORS OF THE UNIVERSITY OF ALBERTA;LOPASCHUK, GARY, DAVID;VEDERAS, JOHN, C.;DYCK, JASON, R. |
发明人 |
LOPASCHUK, GARY, DAVID;VEDERAS, JOHN, C.;DYCK, JASON, R. |
分类号 |
C07C69/74;C07C69/753 |
主分类号 |
C07C69/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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