MODIFIED ADENOVIRUS CONTAINING A STABILIZED ANTIBODY
摘要
The present invention relates generally to the fields of vector biology and gene therapy. The invention is based, in part, on Applicants' discovery that stabilization of the targeting molecule results in successful incorporation of antibody-related molecules into the adenovirus capsid. Accordingly, the present invention relates to the production of recombinant adenoviral vectors containing stabilized antibodies for cell-specific targeting.
申请公布号
WO2006119449(A2)
申请公布日期
2006.11.09
申请号
WO2006US17196
申请日期
2006.05.04
申请人
VECTORLOGICS, INC.;CURIEL, DAVID, T.;KOROKHOV, NIKOLAY